InSolution Tetrahydrouridine

Code: 584223-25MG D2-231

Biochem/physiol Actions

Primary Targetcytidine deaminase

Reversible: yes

Cell permeable: yes

General description

A potent competitive...


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€219.50 EACH
€269.99 inc. VAT

Biochem/physiol Actions

Primary Targetcytidine deaminase

Reversible: yes

Cell permeable: yes

General description

A potent competitive inhibitor of cytidine deaminase. Used in combination with cytosine arabinoside (Ara-C) to assess the anti-leukemic activity and anti-tumor activity of Ara-C in in vitro studies. The solid form of this compound (Cat. No. 584222) is also available.

Legal Information

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Other Notes

Yusa, K., et al. 1995. Biochem. Biophys. Res. Commun.206, 486.r>Bouffard, D.Y., et al. 1993. Biochem Pharmacol.45, 1857.Laliberte, J., et al. 1992. Cancer Chemotherap. Pharmacol.30, 7.Riva, C., et al. 1992. Chemotherapy38, 358.Yusa, K., et al. 1992. J. Biol. Chem.267, 16848.Hanze, A.R. 1967. J. Am. Chem. Soc.89, 6720.

Packaging

25 mg in Glass bottle

Packaged under inert gas

Physical form

A 100 mM (25 mg/879 µL) solution of Tetrahydrouridine (Cat. No. 584222) in H2O.

Reconstitution

Following initial thaw, aliquot and freeze (-70°C). Aliquots are stable for up to 6 months at -70°C.

Warning

Toxicity: Standard Handling (A)

assay≥90% (TLC)
formliquid
InChI keyUCKYOOZPSJFJIZ-XVKVHKPRSA-N
InChI1S/C9H16N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h4-8,12-15H,1-3H2,(H,10,16)/t4-,5?,6-,7-,8-/m1/s1
manufacturer/tradenameCalbiochem®
Quality Level100
shipped indry ice
SMILES stringOC1CCN([C@H]2[C@H](O)[C@H](O)[C@@H](CO)O2)C(N1)=O
storage conditionavoid repeated freeze/thaw cycles, protect from light, OK to freeze
storage temp.−70°C
Cas Number18771-50-1
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